CHRM5

Muscarinic acetylcholine receptor M5 UniProt accession P08912

The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is Pi turnover

Source: UniProt
Cell membrane — Multi-pass membrane protein, Postsynaptic cell membrane — Multi-pass membrane protein
Source: UniProt
  • Muscarinic acetylcholine receptors
  • G alpha (q) signalling events
Source: Reactome via UniProt

Mutations

No mutation information available.

Synthetic Lethal Network

Genes with an experimentally identified or computationally predicted synthetic-lethal relationship to CHRM5, aggregated across our SSL data sources. Click any partner node to view that gene’s page.

Nodes and edges are coloured by the SSL data source. Partners appearing in more than one source are shown in grey.

BioGRID SLOrth SynLethDB MexDrugs Multi-source
Sources: BioGRID, SLOrth, SynLethDB, MexDrugs

Clinical Trials

No clinical trials information available.