Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. Inhibits Wnt signaling
Heterodimer of a large and a small subunit. Interacts (via Cy motif and when phosphorylated at Thr-33) with CCNF; the interaction occurs exclusively in G2 and early M (PubMed:22632967)
No mutation information available.
Genes with an experimentally identified or computationally predicted synthetic-lethal relationship to RRM2, aggregated across our SSL data sources. Click any partner node to view that gene’s page.
Nodes and edges are coloured by the SSL data source. Partners appearing in more than one source are shown in grey.
Total Trials Found: 3
| NCT ID | Condition | Brief Title | Phase | Status |
|---|---|---|---|---|
| NCT03771794 | Healthy | Heart Rate Variability Augmentation With RR2 Neuromodulation Device | NA | UNKNOWN |
| NCT04580953 | Atrial Fibrillation Recurrence | A Prospective Clinical Study Aimed to Assess the Technical Feasibility of RR2 Wearable Home Care Neuromodulation System | NA | COMPLETED |
| NCT05872776 | Paroxysmal Atrial Fibrillation | BEAT AF - Braking Ectopic Atrial Trends In Atrial Fibrillation | NA | RECRUITING |