Drug × Cancer matrix

Each row is a drug, each column a cancer subtype. Cells show the strongest known association for that drug in that cancer: approved clinical trial or blank. The repositionable flag means the drug appears as a synthetic-lethal repositioning candidate in cansar; it’s gene-level, not cancer-level.

Cancer key

GBM — Glioblastoma (CNS astrocytoma grade IV) LUAD — Lung adenocarcinoma SCLC — Small cell lung carcinoma LUSC — Lung squamous cell carcinoma OAC — Oesophageal adenocarcinoma OSCC — Oesophageal squamous cell carcinoma PDAC — Pancreatic ductal adenocarcinoma

Showing 1 of 1 matching drugs for IGFALS — including drugs targeting any of its 2 synthetic-lethal partners , sorted by total cancer coverage.

Drug	Target	Relationship	GBM	LUAD	SCLC	LUSC	OAC	OSCC	PDAC	Reposition	#cancers
disulfiram, copper, alkylating agents	IGFALS	Direct									1

Approval data manually curated from National Cancer Institute and Drugs@FDA. Clinical trials from ClinicalTrials.gov. Repositionable list from cansar.ai.