ORM2

Alpha-1-acid glycoprotein 2 UniProt accession P19652

Functions as a transport protein in the blood stream. Binds various hydrophobic ligands in the interior of its beta-barrel domain. Also binds synthetic drugs and influences their distribution and availability.

Appears to function in modulating the activity of the immune system during the acute-phase reaction

Source: UniProt
Secreted
Source: UniProt

Expressed by the liver and secreted in plasma

Source: UniProt

Contains a beta-barrel that binds various ligands in its interior

Source: UniProt
  • Platelet degranulation
  • Neutrophil degranulation
Source: Reactome via UniProt

Mutations

No mutation information available.

Synthetic Lethal Network

Genes with an experimentally identified or computationally predicted synthetic-lethal relationship to ORM2, aggregated across our SSL data sources. Click any partner node to view that gene’s page.

Nodes and edges are coloured by the SSL data source. Partners appearing in more than one source are shown in grey.

BioGRID SLOrth SynLethDB MexDrugs Multi-source
Sources: BioGRID, SLOrth, SynLethDB, MexDrugs

Clinical Trials

Total Trials Found: 1

NCT ID Condition Brief Title Phase Status
NCT04588220 Preterm Premature Rupture of Membranes Melatonin, Soluble Urokinase-type Plasminogen Activator Receptor, and Orosomucoid 2 Levels in PPROM N/A UNKNOWN